AMD committed up to $5 billion to Anthropic as part of a sweeping computing power deal announced Wednesday, positioning AMD as a critical infrastructure player for one of OpenAI's fiercest rivals while taking direct aim at Nvidia's stranglehold on AI chips. The partnership ties Anthropic's rapidly growing compute needs directly to AMD's MI300 series accelerators and future chip roadmap. Anthropic has been on an infrastructure shopping spree in 2026, scrambling to lock down computing power necessary to train its Claude AI models, and this represents Anthropic's largest single commitment to a chip partner. The deal validates AMD's effort to position itself as a credible alternative in enterprise AI workloads, as Nvidia's H100 and newer H200 chips have become nearly impossible to acquire without year-long waiting lists. The "up to $5 billion" language suggests a phased investment tied to specific milestones or capacity commitments, likely structured as a combination of direct equity investment, infrastructure credits, and potentially revenue-sharing arrangements.