In a 73-minute interview with Ezra Klein, Bill Gates argued that AI has already crossed the bioweapon and cyberattack thresholds, that no supervisory layer exists to stop misuse, and that the industry cannot be trusted to self-regulate. Gates said the cyber and bio thresholds were crossed "early this year," and that the capability exists today for a bioterrorist to "kill hundreds of millions" and for a cyberattack to "scramble all the bank accounts" and shut down the electric grid. He stated the imminent risk is not recursive self-improvement but misuse by humans wielding AI. On cyber, he described coding models finding security bugs in code humans had reviewed for over 20 years and constructing multi-step exploits "in a few minutes," and referenced a program called "Glasswing" meant to give the capability to a few defenders to fix bugs before attackers use it, saying "there's way too much code" for that to work. On bio, he noted the same molecule-design capability that helps the Gates Foundation fund medical research is "ultimate dual use," with someone able to design a pathogen worse than smallpox that takes longer to show symptoms. Gates said AI "makes nuclear weapons look like nothing," called the lack of societal response "complete silence," and said he is redirecting his voice from polio eradication to this issue. The conversation also covered job displacement and his proposed remedies (taxing robot labor, "human reserved" jobs), the Gates Foundation's AI work in global