Anthropic’s Claude Code can now be wired directly to GitHub to automate the entire pull request lifecycle by utilizing native execution hooks and the Model Context Protocol (MCP). This technical integration enables a seamless, vibe-coding workflow where the AI agent autonomously evaluates commits, flags security vulnerabilities, and approves merges. The process requires precise configuration of the command-line interface to ensure security protocols are maintained. Prerequisites include Claude Code CLI installed globally, a valid GitHub Personal Access Token (PAT) with repository read/write permissions, an active Anthropic API key configured in local environment variables, and basic familiarity with Bash scripting and JSON configuration. Step 1 involves initializing the GitHub MCP server by registering it within Claude Code configuration. Step 2 requires configuring a PreToolUse hook that validates the environment state before the agent interacts with GitHub, by creating a `.claude` directory and a `hooks.json` file. Step 3 implements the autonomous review command syntax by invoking Claude using the command `claude --agent "Review pull request #42 for security vulnerabilities and code style compliance."`