Cohere Health built Cohere Policy Studio using Amazon Bedrock AgentCore to digitize clinical policies for prior authorization, a manual healthcare process where approval policies are trapped in static, unstructured formats. The policy content varies by clinical area, geography, line of business, and health plan, and evolves as medicine advances. Cohere Health identified three challenges: per Centers for Medicare & Medicaid Services (CMS) regulations, health plans must support API-based electronic prior authorization by January 2027; America’s Health Insurance Plans (AHIP) commitments require health plans to achieve 80 percent real-time approvals for electronic prior authorization submissions; and each line of business has unique requirements. The application uses a flexible, multi-tenant agentic architecture on AgentCore, which provides multi-tenant isolation, a managed agent runtime, secure MicroVM isolation, unified tool access through AgentCore Gateway, AgentCore Memory, and the Agent Skills open standard. This accelerates policy digitization with workflow management and automatic version tracking while preserving transparency, version control, and human oversight, with medical professionals remaining responsible for clinical review where clinical judgment is required.