Researchers at ICAR-Central Rice Research Institute, Cuttack, have developed and experimentally validated a suite of AI-designed genome-editing platforms for plants, centered on a novel platform called Plant OpenCRISPR-1 (POC1), built upon OpenCRISPR-1 (OC1), an AI-generated nuclease. The team developed POC1-based tools for gene knockout, precise base editing, and prime editing in plants, demonstrating that AI-designed enzymes can function robustly inside plant cells, a capability not previously reported. The POC1 platform achieved editing efficiencies comparable to the widely used SpCas9 system across several rice genes and successfully generated gene disruptions in transformed rice plants. The study, accepted in the international plant science journal New Phytologist, marks a notable advance in agricultural biotechnology. Since OpenCRISPR-1 was released as an open-source nuclease proposed to be freely available for academic research and commercial licensing, it has the potential to broaden access to genome-editing technologies. This research was supported by funding from Indian Council of Agricultural Research (ICAR).