Ai4 2026 will take place from August 4 to 6 at The Venetian in Las Vegas, with organizers having roughly doubled the footprint to nearly a million square feet. The conference lists 12,000-plus attendees, 1,000-plus speakers, and 400-plus exhibitors from more than 90 countries. Ai4 started in 2018 and now runs under CloserStill Media, positioning itself as the largest applied AI conference in the United States. Organizations that took part in 2025 and are expected back include Google, Amazon, Microsoft, NVIDIA, Meta, Databricks, Capital One, Walmart, Pfizer, Johnson & Johnson, JPMorgan, NASA, and Mayo Clinic. The 2026 agenda is built around 20 industry and technical tracks, covering financial services, healthcare, cybersecurity, retail, manufacturing, energy, transportation, national security, insurance, media, AI agents, generative AI, and infrastructure. Two half-day training workshops run on August 3 in partnership with General Assembly, and peer-to-peer discussion groups start Monday, August 2. Recent editions have featured figures such as Geoffrey Hinton and Fei-Fei Li, and the 2026 speaker roster is still being announced week by week.