Geoffrey Hinton and Andrew Ng will share a stage on Wednesday, August 5, at The Venetian in Las Vegas as the headline event of Ai4 2026, which organizers call North America's largest applied AI conference. The three-day event runs August 4 through 6, with pre-conference programming beginning Monday, August 3, including hands-on training with General Assembly at 1:00 PM PT and the Applied AI Research Conference at 9:00 AM PT. The main conference opens Tuesday, August 4, at 7:00 AM PT, with opening keynotes at 8:30 AM PT. Hinton believes the AI industry may be building something that ends humanity, while Ng calls that framing harmful nonsense. The conference's dominant session cluster is agentic AI deployment at scale, reflecting a shift from "what can AI agents do?" to governing and auditing agents making consequential decisions. The first generation of enterprise AI pilot projects has run its course, with companies either moving experiments into production or not. The agenda focuses on production deployment, governance, and failure modes rather than explaining what agents are.